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Helping Pregnant Women With Depression Using TMS Therapy

Dr. Irene Pedraza • March 25, 2024

During pregnancy, the mother's and baby's well-being is of utmost importance. But for some expectant mothers, the joyous anticipation of childbirth can be overshadowed by the dark cloud of depression.


Depression during pregnancy affects approximately 10% of pregnant individuals, posing significant challenges to maternal health and fetal development. Addressing depression during this crucial period isn't just about the mother's mental health; it's about nurturing a healthy environment for the growing life within.


Unfortunately, traditional treatment options like antidepressants or other medications may not always be suitable or safe during pregnancy, leaving many women feeling like they're out of options.


But Transcranial Magnetic Stimulation (TMS) offers hope. It's a safe and effective treatment for pregnant women battling depression. No medication required.


In this blog, we'll dig deeper into maternal depression, the limitations of traditional treatments and explore why TMS can be a safer, more effective option for expecting mothers.

Understanding Depression During Pregnancy

The hormonal shifts, physical changes, and emotional upheavals that accompany pregnancy create a fertile ground for the emergence of depressive symptoms. From feelings of sadness and hopelessness to anxiety and irritability, depression during pregnancy manifests in various forms, casting a shadow over what should be a time of joy and anticipation.


Research demonstrates a correlation between maternal depression and adverse outcomes for both mother and baby. Untreated depression increases the risk of pregnancy complications, such as preterm birth, low birth weight, and preeclampsia. It can also hinder maternal-infant bonding, leading to long-term consequences for the child's emotional and cognitive development.


Left unchecked, depression during pregnancy can cast a pervasive shadow over the entire family unit, perpetuating cycles of emotional distress and relational strain.

Postpartum Depression: Depressive Symptoms After Birth

Postpartum depression is a prevalent condition among mothers, often characterized by various symptoms that significantly impact women's mental well-being following childbirth. These symptoms may include feelings of loss of control over one's life, intense sadness, hopelessness, difficulty making decisions, and episodes of panic attacks and severe anxiety. Affected mothers may also struggle with caring for their newborns.


A consequence of depression during pregnancy and postpartum is its potential to disrupt the mother-child relationship, leading to long-term challenges if the bond fails to form adequately.


Promptly addressing depression during pregnancy mitigates the risk of postpartum depression and attachment issues with children, alleviating broader mental health implications.

Limitations of Traditional Treatment Options 

When it comes to addressing depression during pregnancy, conventional treatment options primarily revolve around psychotherapy and pharmacotherapy. Psychotherapy offers a safe and non-invasive approach to managing depressive symptoms by helping individuals explore and navigate their thoughts, emotions, and behaviors.


On the other hand, pharmacotherapy, often involving the use of selective serotonin reuptake inhibitors (SSRIs), aims to rebalance neurotransmitter levels in the brain to alleviate symptoms of depression.


While psychotherapy and pharmacotherapy have proven efficacy in treating depression, they also come with their own set of limitations and concerns, particularly when it comes to pregnant women. Many expectant mothers hesitate to pursue pharmacological interventions due to potential risks to fetal development, including fears of congenital disabilities, preterm birth, and withdrawal symptoms in newborns.


Additionally, psychotherapy may not always provide rapid relief for severe or acute symptoms, leaving some women feeling overwhelmed and unsupported during a vulnerable time in their lives.

Introducing a Safer Alternative: What is Transcranial Magnetic Stimulation?

Transcranial Magnetic Stimulation is a revolutionary non-invasive neuromodulation therapy that harnesses the power of magnetic pulses to stimulate specific brain regions associated with depression. Unlike traditional treatments like medication or electroconvulsive therapy (ECT), TMS does not involve surgery, anesthesia, or the use of systemic drugs. Instead, it delivers targeted magnetic pulses to the brain, precisely modulating neural activity in areas implicated in mood regulation.


Numerous clinical trials, as demonstrated by a 2019 literature review, found TMS to have a significant, positive impact on women in their second and third trimesters. TMS is also known to:

  • Alleviate symptoms of major depression, even in cases like treatment-resistant depression where other interventions failed.
  • Offer a non-pharmacological alternative for individuals who may be reluctant or unable to tolerate the side effects of medications.

Since TMS does not require the ingestion of substances, it bypasses concerns related to medication exposure during pregnancy, making it an attractive option for expectant mothers struggling with depression.

What happens during a TMS therapy session?

During a session of TMS therapy, you'll be fitted with a headpiece that’ll be placed on your head during treatment. Once it’s placed, an electromagnetic coil will be positioned above the frontal region of your head, emitting the pulsating magnetic fields. This process mirrors that of an MRI, albeit on a significantly smaller scale. These magnetic pulses penetrate about two to three centimeters into the brain to stimulate neurotransmitters that impact mood regulation.


In individuals experiencing major depression, neurotransmitters such as serotonin, dopamine, and norepinephrine are typically imbalanced. TMS works to restore the balance of these chemicals by specifically targeting the area directly beneath the treatment coil, without impacting the entire brain.

Safety of TMS for Pregnant Women

Naturally, mothers want to prioritize the safety of themselves and their unborn children when seeking depression treatment. Fortunately, research and clinical experience show TMS to be well-tolerated and does not pose significant risks to pregnant women or their babies. Healthcare providers carefully assess TMS therapy's potential benefits and risks on a case-by-case basis, ensuring that pregnant patients receive personalized care that prioritizes their well-being.


Despite the overwhelming evidence supporting TMS during pregnancy, common concerns and misconceptions may linger. Some expecting mothers worry that the magnetic pulses used in TMS could harm the developing fetus or induce premature labor. However, TMS does not pose a risk to pregnant women or their babies when administered by trained professionals using appropriate protocols.

TMS Side Effects and Contraindications

While TMS therapy is generally considered safe and well-tolerated, pregnant women should understand the potential side effects and how to manage them during pregnancy.


Common Side Effects of TMS

Side effects are typically mild and temporary and may include:

  • Transient scalp pain
  • Mild headaches
  • Muscle spasms
  • Lightheadedness
  • Tingling sensations

Although uncommon, more severe side effects include seizures and hearing loss.

Healthcare providers monitor pregnant patients closely during TMS sessions and promptly address any concerns or adverse reactions that may arise. Additionally, TMS therapy does not induce a seizure or require anesthesia or sedatives, further minimizing potential risks during pregnancy.

TMS Contraindications

A contraindication refers to any condition, symptom, or circumstance that prohibits the safe execution of a medical procedure or treatment. Pregnancy is not a contraindication for TMS.


TMS contraindications are tattoos containing magnet-sensitive ink or magnetic materials, cochlear implants, metal implants anywhere in the body, aneurysm clips, and cerebral stents.

Benefits of TMS for Pregnant Women with Depression

Transcranial Magnetic Stimulation (TMS) therapy offers a multitude of benefits for pregnant women grappling with depression, providing a ray of hope in what can be a challenging journey. Unlike traditional treatment options that may carry risks or limitations during pregnancy, TMS offers a medication-free alternative that is safe, effective and well-tolerated.


One of the most significant benefits of TMS for pregnant women is its ability to provide relief without adverse effects on the fetus. Unlike medication, which may raise concerns about potential risks to fetal development, TMS targets specific regions of the brain without systemic exposure to substances. This targeted approach minimizes the risk of harm to the fetus.


By offering a safe and productive treatment option, TMS empowers pregnant women to prioritize their mental health without compromising the health and well-being of their unborn child.


Additionally, TMS therapy offers the following benefits for pregnant women with depression:

  • Non-invasive: TMS therapy does not involve surgery or anesthesia, making it a safe and comfortable option for pregnant women.
  • Minimal side effects: Compared to traditional treatments, TMS therapy typically has minimal side effects, allowing pregnant women to undergo treatment without significant discomfort or disruption to their daily lives.
  • Potentially faster results: TMS generally produces quicker results than other treatment options, providing rapid relief from depressive symptoms and improving overall quality of life.

Pregnant women undergoing TMS therapy experience relief from debilitating symptoms of depression, allowing them to reclaim a sense of normalcy during a transformative time.

Explore TMS for Pregnant Women with Depression in Friendswood, TX

TMS can provide relief from depression symptoms while minimizing risks to maternal and fetal health. With proper supervision from healthcare professionals, pregnant women can confidently explore TMS therapy as a safe and effective solution for managing depression during pregnancy.


If you or someone you know is struggling with depression during pregnancy, don't hesitate to reach out about the support you or your loved one deserves. By seeking help and support, you can take proactive steps toward managing depression and nurturing your mental health during this transformative time.


Contact us today to learn why we're the Bay Area's choice for TMS therapy to treat pregnant women with depression. Our team of healthcare professionals is here to provide personalized care to help you confidently navigate your pregnancy.

Cited Sources:


“Maternal depression and child development.” Paediatrics & child health vol. 9,8 (2004): 575-598. doi:10.1093/pch/9.8.575


Shah, Mansi R et al. “Transcranial Magnetic Stimulation for Major Depressive Disorder in Pregnancy: A Literature Review.” Cureus vol. 11,8 e5431. 19 Aug. 2019, doi:10.7759/cureus.5431


Eryılmaz, Gül & Hizli Sayar, Gokben & Özten, Eylem & Gül, Işıl & Yorbik, Özgür & İşiten, Nükhet & Bağcı, Eda. (2014). Follow-Up Study of Children Whose Mothers Were Treated With Transcranial Magnetic Stimulation During Pregnancy: Preliminary Results: Children of rTMS-Treated Pregnant Women. Neuromodulation. 18. 10.1111/ner.12231.

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Studies reveal that children of mothers with PPD are more likely to experience behavioral and emotional challenges . Unfortunately, this knowledge can amplify PPD symptoms, as mothers may feel overwhelmed with guilt or anxiety about the potential impact on their children. Data suggest that postpartum depression affects 10% to 15% of new mothers globally. The prevalence may vary based on factors like socioeconomic status, support systems, and individual history of mental health issues. Despite being relatively common, PPD often goes undiagnosed or untreated due to stigma, lack of awareness, or limited access to resources. The causes of postpartum depression are multifaceted. Biological factors include hormonal changes during and after pregnancy. For example, estrogen and progesterone levels drop sharply after childbirth, potentially affecting mood-regulating brain chemicals. Psychological factors, such as a history of depression or anxiety, also contribute. Additional stressors like sleep deprivation , lack of support , or life changes associated with parenthood can exacerbate these challenges. What Is TMS? Transcranial Magnetic Stimulation (TMS) is a non-invasive treatment for depression that uses magnetic fields to stimulate specific areas of the brain. The U.S. Food and Drug Administration (FDA) approved TMS in 2008 for treating major depressive disorder (MDD) , particularly for individuals who haven't responded to other treatments like medications or therapy. TMS is performed in an outpatient setting , meaning no anesthesia is required. During a session, a technician places a device with an electromagnetic coil against certain brain regions. This coil generates magnetic pulses that create electrical currents in the brain, stimulating nerve cells in brain areas that may be underactive in individuals with depression. Each session typically lasts 30 to 40 minutes , and patients can resume to normal activities immediately afterward. A full course of TMS usually involves three to five sessions per week, over several weeks. How Does TMS Work for Postpartum Depression? TMS works by targeting specific areas of the brain that are less active in people with depression. One key area is the dorsolateral prefrontal cortex (DLPFC), which plays a role in mood regulation, decision-making, and emotional responses. Brain scans show the DLPFC may be dysfunctional in PPD. TMS encourages neuroplasticity —the brain's ability to reorganize itself by forming new neural connections. By enhancing neuroplasticity, TMS helps the brain "reset" patterns of activity linked to depressive symptoms, leading to improved mood and positive ways of thinking. For PPD, TMS offers a promising approach by addressing the underlying neurological factors contributing to the condition. Unlike medications, which alter brain chemistry, TMS directly influences brain activity. This targeted approach reduces the risk of side effects and allows for more precise treatment . Effectiveness of TMS for Postpartum Depression Research supports the effectiveness of TMS for treating postpartum depression. A study published in the Brain Stimulation Journal examined the use of repeated TMS in pregnant and postpartum women with major depressive disorder. The results showed that over 70% of participants experienced significant improvement in their symptoms, and many maintained these benefits over time. Another study published in the Journal of Affective Disorders found TMS improved both depression and anxiety in women with PPD. These mood improvements were sustained three and six months after their treatment, and no serious side effects were reported. TMS is particularly beneficial for individuals who have not responded to traditional therapies like antidepressants or psychotherapy. By offering a new pathway for treatment, TMS provides hope for those who might otherwise feel stuck in their struggle with depression. Is TMS Safe for Postpartum Depression? TMS is generally considered safe, with minimal side effects. Some people may experience headaches or dizziness during or after sessions. However, these side effects are typically temporary and resolve on their own. In rare cases, there have been reports of seizures , hearing loss , and mania following TMS. As such, patients must have a thorough screening before undergoing TMS therapy to ensure they are suitable for treatment. For postpartum mothers, one of the most significant advantages of TMS is that it does not involve medications. This means it doesn't introduce chemicals into the body that could pass into breast milk and affect the baby. Mothers can continue breastfeeding without worrying about potential risks associated with drug-based treatments. Additionally, studies suggest that TMS is safe for women during the peripartum period , including pregnancy and the period after birth. It does not pose risks to the developing fetus or the newborn, making it a suitable option for mothers concerned about the well-being of their children. Exploring TMS at Friendswood Psychiatry Clinic At Friendswood Psychiatry and TMS Clinic , we provide comprehensive mental health services, including TMS therapy, for individuals experiencing depression and other mood disorders. We’re located in Friendswood and are a leading TMS provider in Texas , offering safe and compassionate care to support the unique healing needs of each patient. If you or someone you know is struggling with PPD and you want to know more about our services as a potential solution, be sure to get in touch with one of our team members. You can schedule a free consultation , and we’ll provide you with everything you need to know about this potentially life-changing treatment and how it could serve you.
By Megan Govil January 22, 2025
Transcranial Magnetic Stimulation (TMS) and Electroconvulsive Therapy (ECT) are both effective treatments for mental health disorders, particularly when conventional methods have failed. While both involve stimulating brain cells, they differ significantly in approach, side effects, and suitability for different patients. Understanding these differences can help you make an informed decision about which treatment may be right for you. What Is TMS Therapy? TMS is a non-invasive procedure that uses magnetic pulses to stimulate nerve cells in specific areas of the brain, such as the dorsolateral prefrontal cortex , which are associated with mood regulation and cognition. These areas may be underactive or dysfunctional in people with mental health disorders. By increasing electrical activity, TMS promotes the release of neurotransmitters (chemical messengers) and enhances the activation of these regions. TMS also improves functional connectivity , which refers to the communication between different brain areas. This increased connectivity can help form new patterns of thinking and behavior. During a TMS session, a magnetic coil is placed on the scalp over the target brain regions. Patients remain awake, and the procedure is performed on an outpatient basis, allowing them to return home after their session. A typical session lasts 30 to 40 minutes, and most patients require 20–30 sessions over four to six weeks for optimal results. TMS is particularly effective for individuals who haven’t experienced relief from traditional treatments like medication or therapy. It is most commonly used to treat depression , obsessive-compulsive disorder (OCD) , and addiction , but it is being explored for several other conditions. What Is ECT? ECT is a more invasive treatment that uses controlled electrical currents to induce a brief seizure in the brain. The procedure is performed under general anesthesia, with two electrodes placed on the scalp to deliver the electrical currents. Each session lasts about an hour, including preparation and recovery, while the seizure itself lasts 30–60 seconds. ECT stimulates widespread brain activity and the release of neurotransmitters, often providing rapid relief for severe cases of depression, bipolar disorder, or catatonia. While the exact mechanism of action is not fully understood, ECT’s ability to produce fast results makes it a lifesaving option for individuals with treatment-resistant depression (TRD) or life-threatening symptoms. TMS vs. ECT: Key Differences Treatment Process TMS: Non-invasive and performed on an outpatient basis. Patients remain awake during the session, and no anesthesia or recovery time is required. The treatment is spread out over several weeks. ECT: Requires general anesthesia and is typically administered 2–3 times a week for 6–12 sessions. Recovery time is needed after each session due to the effects of anesthesia and the seizure. Effectiveness TMS: Effective for moderate to severe mental health disorders, with noticeable improvements after a few weeks of treatment. It is especially suited for individuals who have not responded to conventional medication. ECT: Ideal for severe mental health disorders with potentially life-threatening symptoms where rapid relief is essential. Side Effects TMS: Side effects are generally mild and temporary. Common issues include headaches, scalp discomfort, and lightheadedness. Rarely, TMS may cause seizures or hearing issues. ECT: Side effects are more intense and may include short-term memory loss, confusion, fatigue, muscle soreness, and headaches. In rare cases, ECT can cause long-term memory problems or cognitive issues. Who Is a Good Candidate for Each Treatment? Mental Health Conditions TMS: Recommended for moderate to severe depression and OCD when other treatments have failed. It is also useful for individuals struggling to quit smoking or other potentially life-threatening addictions. ECT: Typically reserved for severe, treatment-resistant depression (TRD), bipolar disorder, schizophrenia, and catatonia. Treatment History TMS: Suitable for those who have tried antidepressants or talk therapy without success. It is also a good option for people struggling to overcome addiction despite multiple therapies. ECT: Often considered when multiple other treatments, including TMS, have failed or when a faster response is critical. Medical Eligibility TMS: Does not require general anesthesia, making it safer for patients with certain medical conditions. ECT: Since it involves anesthesia, additional medical evaluations may be required for individuals with cardiovascular or respiratory issues. Explore TMS Treatment Options at Friendswood Psychiatry Clinic At Friendswood Psychiatry Clinic, we offer advanced treatments like TMS to support your journey toward improved mental health. Our compassionate team designs personalized treatment plans tailored to your unique needs, ensuring the best possible outcomes. To provide a holistic approach, we also offer talk therapies that can be integrated into your program, helping you achieve lasting well-being and a better quality of life. If you’d like to learn more, be sure to book a free consultation with one of our team members.
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